analytica conference 2020

Session I

Biopharmaceuticals

  • Characterization and Developability of multispecific Antibodies.
  • Antibody Drug Conjugates – Challenges, Concepts and Opportunities
  • Toxin-armed Antibodies for Effective Tumour Cell Killing
  • Biomarker Immunossays in Multiplex and their Application in Preclinical and Clinical Research
Session I

ABC: Digital Analytical Sciences (Repeated)

  • Good vibrations: towards rapid screening of energetic materials properties
  • Digital Transformation of the Analytics Lab - A Key Factor to Drive Innovation
  • Chemometrics or machine learning for the analysis of Raman spectroscopic related data?
  • Digital Detective Work: Connecting Cheminformatics, Mass Spectrometry and our Environment
Session III

Chromatography and Mass Spectrometry: Anything New? III (Repeated)

  • Pushing the peak capacity boundaries in GCxGC
  • Hyper-fast flow-field thermal gradient GC: Latest developments, applications and perspectives
  • Extending metabolomics by full-scale compound identification
  • GC-MS as tool to study tumor metabolism
Session I

Biopharmaceuticals (Repeated)

  • Characterization and Developability of multispecific Antibodies.
  • Antibody Drug Conjugates – Challenges, Concepts and Opportunities
  • Toxin-armed Antibodies for Effective Tumour Cell Killing
  • Biomarker Immunossays in Multiplex and their Application in Preclinical and Clinical Research
Session I

Analysis of Pathogens and Antibiotic-resistant Bacteria (Repeated)

  • Modern analytical methods for pathogens and antibiotic resistant bacteria
  • Molecular fecal pollution diagnostics for water quality testing: from polymerase chain reaction to rapid isothermal amplification to detect genetic fecal markers
  • Antibiotic Resistances - a rising challenge
  • MALDI-TOF MS for rapid identification of microbial contaminations in drinking water systems
  • Real-time and remote monitoring of a drinking water distribution testbed in Singapore
Session I

Chromatography and Mass Spectrometry: Anything New? I - Eberhard-Gerstel-Award Session - (Repeated)

  • Analysis of complex samples with LCxLC, LC-IMS or µLC+LC-IMS coupled to qTOF-MS: Who is the winner?
  • Ion Source Development for Ambient Mass Spectrometry
  • Charge Retention/Charge Depletion in ESI-MS
  • Eberhard-Gerstel Award Lecture: 2D in Seconds: Coupling of Chip-HPLC with Ion Mobility Spectrometry
Session III

Metabolomics (Repeated)

  • Retention time indexing as an approach to standardize reporting of retention data in metabolomics
  • Applications of Stable Isotope Labelling in Metabolomics and lipidomics
  • Metabolomics for personalized medicine: challenges related to analytical chemistry
  • Relationships between cellular metabolite and drug uptake and transporter expression profiles
Session III

ABC: Bioanalytics II - Analytics Enabling the Concept of Anywhere Care (Repeated)

  • Data fusion strategies to combine process sensor and NIR-based multivariate model outputs for Multivariate Statistical Process Control
  • Optical ensing with dipsticks in food and water analysis
  • Mycotoxin mimotopes: exploring alternative immunosensing approaches
  • Point of Care Diagnostics in Low Income Countries: the challenge of affordability
Session II

Metrology Meets Life Science (Repeated)

  • Reference measurement procedures for intact proteins using inductively coupled plasma mass spectrometry (ICP-MS)
  • A Reference System Approach for Cell and Particle Counting
  • Development of certified reference materials for in–vitro diagnostics.
  • Metrology for support of nucleic acid analysis in health and food
Session II

Non-target Screening in Future Water Monitoring (Repeated)

  • Strategies for the characterization and identification of unknown water contaminants
  • Do we need standardization in non-target screening?
  • High Resolution Mass Spectrometric non-target screening of emerging contaminants in the environment-Development of methods and workflows and their application in wide-scope monitoring studies and exposure assessment
  • Non-target screening of organic micro-pollutants to support risk based monitoring strategies in drinking water sources
Session II

ABC: Bioanalytics I - Nanomaterials in BioAnalysis (Repeated)

  • Innovative plasmonic nanostructures for vibrational biosensing
  • Carbon based nanostructures: an electoanalytical and biomedical perspective
  • Janus emulsions as transducers in liquid biosensing platforms
  • Engineered nanofiber hybrids as multifunctional 3D-interfaces for electrobioanalytical applications
Session II

Chromatography and Mass Spectrometry: Anything New? II (Repeated)

  • Comparison of sampling and chromatographic retention mechanism for the screening of emerging contaminants
  • Developing multi-dimensional separations and separation systems
  • Development a Microfluidic Device for Cell Capture, Sorting and Metabolite Analysis with Mass Spectrometry
Session III

Liquid Profiling to Guide Cancer Therapies (Repeated)

  • Liquid Biopsy in Oncology - From research to clinical practice
  • Liquid profiling of head and neck cancer patients with plasma and saliva
  • Liquid Biopsy – A Molecular Pathology Perspective
Session I

Data Management Aspects of Human Biobanking

  • Pre-Analytics: A paradigm shift towards predictive sample entry
  • To merge clinical data and biobank data with other information sources – inspiration from the Swedish U-CAN project and the IT-solution “Octopus”
  • Qatar Biobank: A Paradigm of Translating Biobank Science into Evidence-Based Health Care Interventions
Session I

High Resolution Mass Spectrometry: Technologies and Applications I

  • 2D-FTICR MS, heritage and archeological samples
  • Direct thermal analysis methods as sample introduction for high-resolution mass spectrometry – Molecular-level description of heavy petroleum fractions
  • High performance analysis of complex mixtures by high-field FT-Orbitrap MS: exploring the carbon space
  • 21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometry: Performance Benchmarks and Applications
Session I

Current and Future Challenges in Analytical Spectrometry I

  • Bunsen-Kirchhoff Award Lecture: Raman Microspectroscopy for Environmental Analysis
  • Multimodal multiphoton microspectroscopy for bioanalytics
  • Raman plus isotopes for antibiotic susceptibility and heteroresistance testing
  • Analytical Chemistry in Times of Grand Challenges
Session I

Biobased and Biomimetic Sensing (Repeated)

  • CRISPR powered electrochemical biosensor for nucleic acid diagnostics
  • Electrolyte Gated Organic Transistors for label-free biosensing
  • Towards a biomimetic smell sensor – Applying lessons from nature: from fundamentals to unconventional IoT-applications
  • SERS-based optofluidics: towards real time and automated food pathogen detection platforms
Session II

Patient Safety and Test Utilization

  • Diversified Implementation of Test Utilization Management Programs in Clinical Laboratories Worldwide
  • Standardized lab requesting and reporting
  • How lab tests improve measurable outcome: Experiences with up to date GFR-based adjustments of drug dosing
Session II

High Resolution Mass Spectrometry: Technologies and Applications II

  • Measuring mass of molecules: from atoms to molecular machines
  • Disentangling proteomes with high-resolution Orbitrap mass spectrometry
  • Fast proteomic analysis of clinical samples
  • Maximizing the value of Orbitrap FTMS through advanced data acquisition and processing
Session II

Current and Future Challenges in Analytical Spectrometry II

  • Natural Nanoparticles – a challenge for every environmental analytical chemist
  • Nanomaterials for surface enhanced vibrational spectroscopy
  • ICP-TOF-MS as a tool for multi element fingerprinting in single cells and particles
  • From bulk to single cell analysis of biomarkers by ICP-MS.
Session II

Targeted and Non-targeted Foodomics Correlated to Bioactivity and Authenticity (Repeated)

  • Peptide profiling of milk: analytical strategies, identification of bioactive peptides and fingerprinting of product authenticity
  • Developing targeted and non-targeted authenticity- and quality-tests with analytical ecosystems: Application to grains
  • Mass Spectrometry Imaging as a tool to visualize mycotoxins and plant defence-related metabolites
Session III

Liquid Profiling to Guide Cancer Therapies

  • Liquid profiling of head and neck cancer patients with plasma and saliva
  • Liquid Biopsy in Oncology - From research to clinical practice
  • Liquid Biopsy – A Molecular Pathology Perspective
Session III

High Resolution Mass Spectrometry: Technologies and Applications III

  • High Resolution TOFMS: Past, Present and Future
  • The application of electron ionization in combination with different inlet techniques for high resolution time-of-flight mass spectrometry
  • Characterization of highly complex organic mixtures by high-resolution time of flight mass spectrometry coupled to ion mobility spectrometry
Session III

Current and Future Challenges in Analytical Spectrometry III

  • Cascade Lasers in Chem/Bio Sensing:Quo Vadis?
  • Molecular images and differentiation of isomers based on mass spectrometry of biological samples
  • Multi-Method Combinations of La-Icp-Ms for Spatially-Resolved Chemical Analysis
  • Towards Metal Speciation Imaging
Session III

Pushing the Limits of Separation: Still Much to Discover (Repeated)

  • Selectivity vs. Plate Count: From long columns and orthogonal selectivity - Where are the limits?
  • Reversed Phase vs. Hydrophilic Interaction Liquid Chromatography. Or even together?
  • Current Trends in Ion Chromatography
  • JFK Huber Name Award Lecture (ASAC): Chiral Separations in the Twenty-first Century
Session III

High Resolution Mass Spectrometry: Technologies and Applications III (Repeated)

  • The application of electron ionization in combination with different inlet techniques for high resolution time-of-flight mass spectrometry
  • High Resolution TOFMS: Past, Present and Future
  • Characterization of highly complex organic mixtures by high-resolution time of flight mass spectrometry coupled to ion mobility spectrometry
Session II

Emerging Topics in Analytical Toxicology, Forensics, and Doping Control II (Repeated)

  • Mass Spectrometry Imaging in Forensic Research and Practice
  • Fingerprint Development Methods for Touch Chemistry of Drugs and Explosives Using MALDI/TOF MS
  • Current Role of OMICS in Analytical Toxicology
  • Role of Metabolomics in the Antidoping Toolbox
Session II

Current and Future Challenges in Analytical Spectrometry II (Repeated)

  • ICP-TOF-MS as a tool for multi element fingerprinting in single cells and particles
  • From bulk to single cell analysis of biomarkers by ICP-MS.
  • Natural Nanoparticles – a challenge for every environmental analytical chemist
  • Nanomaterials for surface enhanced vibrational spectroscopy
Session III

Fishing for Protein Biomarkers - Cutting-edge Immunoassays (Repeated)

  • Mass spectrometry-based immunoassays for the analysis of drug-induced organ injury biomarker proteins
  • Profiling of cellular signal transduction pathways using a multiplexed Western-Blot
  • Affinity proteomics for blood-based precision medicine
  • Ultra-sensitive immunoassays in Alzheimer’s disease
Session III

Emerging Topics in Analytical Toxicology, Forensics, and Doping Control III (Repeated)

  • Bioanalysis of therapeutic proteins – What is the „correct“ result and what is the right technology?
  • Alternative Tools for Metabolism Studies of Drugs of Abuse
  • Novel Strategies for Microsampling-Dried Matrix Spots and Exhaled Breath
Session III

Current and Future Challenges in Analytical Spectrometry III (Repeated)

  • Cascade Lasers in Chem/Bio Sensing:Quo Vadis?
  • Molecular images and differentiation of isomers based on mass spectrometry of biological samples
  • Multi-Method Combinations of La-Icp-Ms for Spatially-Resolved Chemical Analysis
  • Towards Metal Speciation Imaging
Session II

Lipidomics (Repeated)

  • Bringing Lipidomics Results into Biological Context
  • F2-Isoprostanes as biomarkers of oxidative stress in human disease
  • Combination of LC-MS and MS imaging for the lipid profiling of biological tissues
  • Accurate lipid species quantification in FTMS
Session I

Advanced Microscopy (Repeated)

  • Imaging single-cell metastases in whole mice
  • Quantitative analysis of cytoplasmic calcium levels in vivo reveals heterogeneity of plasma cells
  • Advanced imaging techniques to visualize TNF-induced changes in secondary lymphoid organs and bone in an experimental model of spondyloarthritis
  • Title tba
Session II

High Resolution Mass Spectrometry: Technologies and Applications II (Repeated)

  • Fast proteomic analysis of clinical samples
  • Measuring mass of molecules: from atoms to molecular machines
  • Disentangling proteomes with high-resolution Orbitrap mass spectrometry
  • Maximizing the value of Orbitrap FTMS through advanced data acquisition and processing
Session I

Emerging Topics in Analytical Toxicology, Forensics, and Doping Control I (Repeated)

  • Role of IRMS in Life Sciences with Focus on Forensic Sciences
  • Power of IRMS in Doping Control
  • Profiling of New Psychoactive Substances by IRMS
Session I

High Resolution Mass Spectrometry: Technologies and Applications I (Repeated)

  • Direct thermal analysis methods as sample introduction for high-resolution mass spectrometry – Molecular-level description of heavy petroleum fractions
  • High performance analysis of complex mixtures by high-field FT-Orbitrap MS: exploring the carbon space
  • 21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometry: Performance Benchmarks and Applications
  • 2D-FTICR MS, heritage and archeological samples
Session I

Current and Future Challenges in Analytical Spectrometry I (Repeated)

  • Multimodal multiphoton microspectroscopy for bioanalytics
  • Raman plus isotopes for antibiotic susceptibility and heteroresistance testing
  • Analytical Chemistry in Times of Grand Challenges
  • Bunsen-Kirchhoff Award Lecture: Raman Microspectroscopy for Environmental Analysis
Session I

Biobased and Biomimetic Sensing

  • Towards a biomimetic smell sensor – Applying lessons from nature: from fundamentals to unconventional IoT-applications
  • CRISPR powered electrochemical biosensor for nucleic acid diagnostics
  • Electrolyte Gated Organic Transistors for label-free biosensing
  • SERS-based optofluidics: towards real time and automated food pathogen detection platforms
Session I

Pushing the Limits of Separation: Still Much to Discover

  • Current Trends in Ion Chromatography
  • Reversed Phase vs. Hydrophilic Interaction Liquid Chromatography. Or even together?
  • JFK Huber Name Award Lecture (ASAC): Chiral Separations in the Twenty-first Century
  • Selectivity vs. Plate Count: From long columns and orthogonal selectivity - Where are the limits?
Session I

ABC: Digital Analytical Sciences

  • Digital Transformation of the Analytics Lab - A Key Factor to Drive Innovation
  • Good vibrations: towards rapid screening of energetic materials properties
  • Chemometrics or machine learning for the analysis of Raman spectroscopic related data?
  • Digital Detective Work: Connecting Cheminformatics, Mass Spectrometry and our Environment
Session I

Emerging Topics in Analytical Toxicology, Forensics, and Doping Control I

  • Role of IRMS in Life Sciences with Focus on Forensic Sciences
  • Profiling of New Psychoactive Substances by IRMS
  • Power of IRMS in Doping Control
Session I

Advanced Microscopy

  • Title tba
  • Quantitative analysis of cytoplasmic calcium levels in vivo reveals heterogeneity of plasma cells
  • Imaging single-cell metastases in whole mice
  • Advanced imaging techniques to visualize TNF-induced changes in secondary lymphoid organs and bone in an experimental model of spondyloarthritis
Session II

Lipidomics

  • F2-Isoprostanes as biomarkers of oxidative stress in human disease
  • Combination of LC-MS and MS imaging for the lipid profiling of biological tissues
  • Accurate lipid species quantification in FTMS
  • Bringing Lipidomics Results into Biological Context
Session II

Non-target Screening in Future Water Monitoring

  • High Resolution Mass Spectrometric non-target screening of emerging contaminants in the environment-Development of methods and workflows and their application in wide-scope monitoring studies and exposure assessment
  • Non-target screening of organic micro-pollutants to support risk based monitoring strategies in drinking water sources
  • Strategies for the characterization and identification of unknown water contaminants
  • Do we need standardization in non-target screening?
Session II

ABC: Bioanalytics I - Nanomaterials in BioAnalysis

  • Engineered nanofiber hybrids as multifunctional 3D-interfaces for electrobioanalytical applications
  • Janus emulsions as transducers in liquid biosensing platforms
  • Innovative plasmonic nanostructures for vibrational biosensing
  • Carbon based nanostructures: an electoanalytical and biomedical perspective
Session II

Emerging Topics in Analytical Toxicology, Forensics, and Doping Control II

  • Current Role of OMICS in Analytical Toxicology
  • Role of Metabolomics in the Antidoping Toolbox
  • Fingerprint Development Methods for Touch Chemistry of Drugs and Explosives Using MALDI/TOF MS
  • Mass Spectrometry Imaging in Forensic Research and Practice
Session III

Chromatography and Mass Spectrometry: Anything New? III

  • Pushing the peak capacity boundaries in GCxGC
  • Extending metabolomics by full-scale compound identification
  • GC-MS as tool to study tumor metabolism
  • Hyper-fast flow-field thermal gradient GC: Latest developments, applications and perspectives
Session II

Chromatography and Mass Spectrometry: Anything New? II

  • Development a Microfluidic Device for Cell Capture, Sorting and Metabolite Analysis with Mass Spectrometry
  • Developing multi-dimensional separations and separation systems
  • Comparison of sampling and chromatographic retention mechanism for the screening of emerging contaminants
Session I

Chromatography and Mass Spectrometry: Anything New? I - Eberhard-Gerstel-Award Session -

  • Ion Source Development for Ambient Mass Spectrometry
  • Charge Retention/Charge Depletion in ESI-MS
  • Eberhard-Gerstel Award Lecture: 2D in Seconds: Coupling of Chip-HPLC with Ion Mobility Spectrometry
  • Analysis of complex samples with LCxLC, LC-IMS or µLC+LC-IMS coupled to qTOF-MS: Who is the winner?
Session I

Data Management Aspects of Human Biobanking (Repeated)

  • Qatar Biobank: A Paradigm of Translating Biobank Science into Evidence-Based Health Care Interventions
  • To merge clinical data and biobank data with other information sources – inspiration from the Swedish U-CAN project and the IT-solution “Octopus”
  • Pre-Analytics: A paradigm shift towards predictive sample entry
  • Ethical principles in biobanking – has there something changed with the GDPR?
Session III

Trends in Electroanalysis

  • Capacitive field-effect sensors for label-free biosensing
  • Miniaturized platforms for electrochemical (bio) sensing of (glyco) proteins in clinical diagnosis
  • Electromembrane extraction – past, present and future
  • Investigation of thymine oxidation by electrochemistry-mass spectrometry
Session III

Patient Safety and Test Utilization (Repeated)

  • Diversified Implementation of Test Utilization Management Programs in Clinical Laboratories Worldwide
  • Standardized lab requesting and reporting
  • How lab tests improve measurable outcome: Experiences with up to date GFR-based adjustments of drug dosing
Session III

ABC: Bioanalytics II - Analytics Enabling the Concept of Anywhere Care

  • Data fusion strategies to combine process sensor and NIR-based multivariate model outputs for Multivariate Statistical Process Control
  • Optical ensing with dipsticks in food and water analysis
  • Mycotoxin mimotopes: exploring alternative immunosensing approaches
  • Point of Care Diagnostics in Low Income Countries: the challenge of affordability
Session III

Analysis of Pathogens and Antibiotic-resistant Bacteria

  • Real-time and remote monitoring of a drinking water distribution testbed in Singapore
  • MALDI-TOF MS for rapid identification of microbial contaminations in drinking water systems
  • Modern analytical methods for pathogens and antibiotic resistant bacteria
  • Molecular fecal pollution diagnostics for water quality testing: from polymerase chain reaction to rapid isothermal amplification to detect genetic fecal markers
  • Antibiotic Resistances - a rising challenge
Session III

Emerging Topics in Analytical Toxicology, Forensics, and Doping Control III

  • Novel Strategies for Microsampling-Dried Matrix Spots and Exhaled Breath
  • Bioanalysis of therapeutic proteins – What is the „correct“ result and what is the right technology?
  • Alternative Tools for Metabolism Studies of Drugs of Abuse
Session III

Fishing for Protein Biomarkers - Cutting-edge Immunoassays

  • Ultra-sensitive immunoassays in Alzheimer’s disease
  • Mass spectrometry-based immunoassays for the analysis of drug-induced organ injury biomarker proteins
  • Profiling of cellular signal transduction pathways using a multiplexed Western-Blot
  • Affinity proteomics for blood-based precision medicine
Session II

Metrology Meets Life Science

  • A Reference System Approach for Cell and Particle Counting
  • Development of certified reference materials for in–vitro diagnostics.
  • Metrology for support of nucleic acid analysis in health and food
  • Reference measurement procedures for intact proteins using inductively coupled plasma mass spectrometry (ICP-MS)
Session II

Chemometrical Methods - An Option for Data Mining from Analytical Data Sets

  • Wo kommt denn das Rauschen her? Störgrößen und Unsicherheit verfolgen entlang des Analysengangs
  • Chemometrics for Process Spectroscopy
  • Multivariate Ansätze in der Auswertung (hyper)spektraler Daten für die Mikroplastikanalytik – Möglichkeiten und Grenzen
  • Retrospektive Prüfung der Probennahmeunsicherheit anhand von analytischen Ergebnissen mittels chemometrischer Methoden
Session II

Targeted and Non-targeted Foodomics Correlated to Bioactivity and Authenticity

  • Mass Spectrometry Imaging as a tool to visualize mycotoxins and plant defence-related metabolites
  • Developing targeted and non-targeted authenticity- and quality-tests with analytical ecosystems: Application to grains
  • Peptide profiling of milk: analytical strategies, identification of bioactive peptides and fingerprinting of product authenticity
Session III

Metabolomics

  • Applications of Stable Isotope Labelling in Metabolomics and lipidomics
  • Metabolomics for personalized medicine: challenges related to analytical chemistry
  • Relationships between cellular metabolite and drug uptake and transporter expression profiles
  • Retention time indexing as an approach to standardize reporting of retention data in metabolomics